VIAGRA AND BLOOD CIRCULATION

Viagra is one of the best-known medications of all times. Almost every adult male in America heard about it and can say how it works. From the very beginning of the appearance of Viagra in 1998, Bob Dole, the former presidential candidate of the Republican Party, spoke as the supporter of this drug.

At that time the production of counterfeit pills increased, and jokes about Viagra became a permanent feature of American pop culture. What is so special about the “little blue pill”? It quite simply, it helps to man who taking it to reach erection.

How Viagra do it? And why it works only when man is excited? If we touched this theme we need to say what in the first place affects erection? In this article we will answer these and many other questions.
This is a fascinating story; it will talk about the structure of the human body and about methods that scientists use to control its separate parts with use of grugs. In the case of Viagra such effect is observed on penis.

ANATOMY OF PENIS

For many people talk about genital is unpleasant. This part of body is not discussed in public (at least, not in the decent society). However, the penis performs a specific function in the organism, and we will treat it just at this point. There are two tasks with which he must deal:

  • urination (voiding);
  • ejaculation (release of semen);

Viagra is designed to solve the second problem. When the man’s body is working properly ejaculation represents a three-stage process that includes:

  • sexual arousal;
  • erection as response to stimulation;
  • ejaculation as a result of stimulation of the penis.

Sounds enough simple, but in many cases, the second stage is not attainable, and after it the third stage is also impossible. Even with a stimulation, an erection may not occur. To find out why it happens, it is necessary to understand the process of erection.

ERECTION TECHNOLOGY

If you decide move any part of your body, you do it with the help of muscles. When you wiggle your arms and legs fingers, hands and feet, muscle do their job properly. Even when you show your language to someone you do this with the help of muscles:

  • you think about moving parts of the body;
  • appropriate muscles contract;
  • limb moves.

Muscles allow us to transfer our body while controlling the moving. However, in the erection process muscle contraction do not participate, for this is used the pressure. Perhaps the most simple way to show it is to illustrate this process with the help of a balloon. If you let the air out of the ball it will become sluggish.

Once you inflate it again, the ball will stretch and become elastic and rigid. The penis consists ot the corpus cavernosum, in cells of which during erection the blood is delayed. Thus, a state of penis is change depending on blood flow:

  • when the arteries that bring blood to the cavernous bodies are somewhat constricted, while the veins that carry outflow of blood are expanded, there are no erection;
  • when a man is excited, the arteries are dilated so that blood under pressure could quickly fill the cavernous bodies and veins are narrowed and the penis comes into a state of erection.

If the arteries that provide blood flow to the penis do not expand, an erection is impossible. This is the main cause of erectile dysfunction (ED). To solve the problem of erectile dysfunction in cases where its cause is a bad circulation it is necessary to expand arteries. Let’s see how this can be done and how it was done until release of Viagra.

Before the invention of Viagra men were injected with some medications. The first real breakthrough in the fight against erectile dysfunction was in 1983. Until that time it was believed that the inability to achieve an erection has primarily psychological nature. This concept collapsed at a meeting of the American Urological Association in Las Vegas (1983), when Dr. Giles Brindley introduced himself a preparation about which he gave a lecture, and then lowered his pants to show to the incredulous audience of one of the first
erections caused by medication.

How does Ventolinum atcs? – the same drug. It causes muscle relaxation. There are several types of muscle tissue, scientists distinguish:

  • skeletal muscles;
  • heart muscle;
  • smooth muscles (in blood vessels, intestines and stomach) that act involuntarily.

These smooth muscles play a key role in the erection, and phentolamine is a drug that causes relaxation of smooth muscles. In 1983, the reason why the injection of phentolamine caused an erection, especially interested urologists, because no one thought about it before. That’s what happened then to Brindley:

Arteries of his penis were narrowed and continued to hold the blood from entering the covernosa bodies;
after injection he made the smooth muscles in the walls of the arteries of his penis relaxed and expanded;
blood began to flow into the erectile tissues, blood pressure increased, that leaded to an instant erection.

Since the mid 1980s, the introduction of the drug that relaxes smooth muscles, has become for men the only way to solve erectile dysfunction problem. Viagra make this process much easier: its effect is similar to the effect of phentolamine, but in this case the man does not have to do the injection.

Another advantage of Viagra front of injection of phentolamine is that it causes an erection only when the man is in a state of sexual arousal. Phentolamine, contrary, leads to immediate and uncontrolled erection. Why an action of these pills is applied only to smooth muscle of the penis and not to the entire orgamism, and only when a person is excited? Only a clear understanding of how the blood flow works in the
organism can help you to find answers to these questions.

CIRCULATION IN THE HUMAN ORGANISM

To understand how is produced a drug that acts specifically on the smooth muscle of the penis, it is worth think about circulation in our body. It is only one pump in it – the heart. However, different parts of body in the same time have to receive different amounts of blood.

For example if you run a marathon, your body needs to send more blood to the muscles of your arms and legs, that can lead to a reduction of the amount of the blood that enters, for example, in the stomach (or other unused parts of body at the moment) in order to conserve oxygen. In other words, our heart needs a set of valves that it can use to increase and decrease blood flow to certain parts of the body, and our brain needs a way to control them. A control mechanism of these valves has a chemical nature:

  • The brain sends a signal to a particular nerve fiber. It ends with a neural cell in the artery proximal to the site where should be altered blood flow;
  • These nerve cells produce nitric oxide, which enters the bloodstream and the surrounding cells;
  • Nitric oxide stimulates the production of the enzyme by neighboring cells, this enzyme contributes to the development of a special substance;
  • under the influence of which the smooth muscles that line the wall of the artery relax, resulting in enhanced blood flow.

VIAGRA

Viagra is a medication that brought their creators an extraordinary success. That is why It is not surprising that other pharmaceutical companies want to grab a piece of that glory. Thus were developed new chemicals and created two new drugs: Cialis (tadalafil) and Levitra (vardenafil).

Cialis and Levitra work in the same way as Viagra: helping men who have problems with maintaining an erection due to problems with the blood flow, and acting only when a man is sexually excited. As the basis for the action of these medications are different chemicals, Viagra, Cialis and Levitra have some differences. For example:

Cialis can cause muscle pain and back pain in some patients (for Levitra or Viagra this side effect is not typical). The action of Viagra lasts for about four hours, while Levitra retains in the blood for five hours.

Cialis remains in the body much longer (it has a 17.5 hour half-life) and thus may be effective more than a day. For this reason, Cialis, as expected, quite soon will replace Viagra out of the market. What is its nickname? “A weekend pill”.

Cialis starts acting faster than Viagra or Levitra – about 15 minutes after taking. According to some reports, fatty food has an impact on the effect of Viagra and Levitra in the organism, but on the effectiveness of
Cialis its use does not affect. At the stage of development there are many new drugs.

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